Top 10: August 2020

Home | Daily TOP 10 | April | May | June | July | August | TOP 10 BOOK (PDF)

 

By Christian Hoffmann &
Bernd S. Kamps

31 August

The Top 10 >>>

  • Detection of SARS-CoV-2 in raw and treated wastewater in Germany – Suitability for COVID-19 surveillance and potential transmission risks
  • High rates of SARS-CoV-2 seropositivity in nursing home residents
  • High Through-Put Assay For Circulating Antibodies Directed Against The S Protein Of Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-Cov-2)

and more >>>

30 August

The Top 10 >>>

  • Two metres or one: what is the evidence for physical distancing in covid-19?
  • The psychology of protecting the UK public against external threat: COVID-19 and the Blitz compared
  • Anticoagulation, Mortality, Bleeding and Pathology Among Patients Hospitalized with COVID-19: A Single Health System Study

and more >>>

29 August

The Top 10 >>>

  • Saliva or Nasopharyngeal Swab Specimens for Detection of SARS-CoV-2
  • SARS-CoV-2 Infections Among Children in the Biospecimens from Respiratory Virus-Exposed Kids (BRAVE Kids) Study
  • The coronavirus is most deadly if you are older and male — new data reveal the risks

and more >>>

28 August

The Top 10 >>>

  • Impact of Famotidine Use on Clinical Outcomes of Hospitalized Patients With COVID-19
  • Increased Risk of COVID-19 Among Users of Proton Pump Inhibitors
  • Clinical Features and Outcome of SARS-CoV-2 Infection in Neonates: A Systematic Review

and more >>>

27 August

The Top 10 >>>

  • Universal trends in human cough airflows at large distances featured
  • Preventing and Mitigating SARS-CoV-2 Transmission — Four Overnight Camps, Maine, June–August 2020
  • SARS-CoV-2 Virus Culture and Subgenomic RNA for Respiratory Specimens from Patients with Mild Coronavirus Disease

and more >>>

26 August

The Top 10 >>>

  • COVID-19 re-infection by a phylogenetically distinct SARS-coronavirus-2 strain confirmed by whole genome sequencing
  • An inflammatory cytokine signature predicts COVID-19 severity and survival
  • Lung transplantation for COVID-19-associated acute respiratory distress syndrome in a PCR-positive patient

and more >>>

25 August

The Top 10 >>>

  • Human-viral chimera: a novel protein affecting viral virulence and driving host T-cell immunity
  • Knowledge transfer for large-scale vaccine manufacturing
  • COVID-19 prevalence and mortality in patients with cancer and the effect of primary tumour subtype and patient demographics: a prospective cohort study

and more >>>

24 August

Top 20 >>>

Top 20 on Face Masks

Almost all organizations recommend masks for the general public. Unfortunately, earlier in the pandemic, many did exactly the opposite – due to limited data but also due to concerns about diminished mask supply for healthcare workers and out of fear that masked individuals might be tempted to ignore rules of social distancing. In addition, conflicting national guidelines have led to variable public compliance.

Do you need some arguments to convince your patients to wear a face mask? Here we present the Top 20 studies on their effectiveness and/or efficacy.

more >>>

23 August

The Top 10 >>>

  • How Do Presenting Symptoms and Outcomes Differ by Race/Ethnicity Among Hospitalized Patients with COVID-19 Infection? Experience in Massachusetts
  • A cross-reactive human IgA monoclonal antibody blocks SARS-CoV-2 spike-ACE2 interaction
  • Early detection of elevated cardiac biomarkers to optimise risk stratification in patients with COVID-19

and more >>>

22 August

The Top 10 >>>

  • Clinical course and factors associated with outcomes among 1904 patients hospitalized with COVID-19 in Germany: an observational study
  • The Worst Patient—A Physician With COVID-19
  • Effect of Remdesivir vs Standard Care on Clinical Status at 11 Days in Patients With Moderate COVID-19: A Randomized Clinical Trial

and more >>>

21 August

The Top 10 >>>

  • Assessment of SARS-CoV-2 Transmission on an International Flight and Among a Tourist Group
  • SARS-CoV-2 Infection Among Community Health Workers in India Before and After Use of Face Shields
  • Pediatric SARS-CoV-2: Clinical Presentation, Infectivity, and Immune Responses

and more >>>

20 August

The Top 10 >>>

  • Prevalence of SARS-CoV-2 asymptomatic infections in two large academic health systems in Wisconsin
  • SARS-CoV-2-specific T cells exhibit phenotypic features of robust helper function, lack of terminal differentiation, and high proliferative potential
  • Loss of Bcl-6-expressing T follicular helper cells and germinal centers in COVID-19A single-dose intranasal ChAd vaccine protects upper and lower respiratory tracts against SARS-CoV-2

and more >>>

19 August

The Top 10 >>>

  • In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges
  • Effects of a major deletion in the SARS-CoV-2 genome on the severity of infection and the inflammatory response: an observational cohort study
  • The antibiotic paradox: why companies can’t afford to create life-saving drugs

and more >>>

18 August

The Top 10 >>>

  • Neutralizing antibodies correlate with protection from SARS-CoV-2 in humans during a fishery vessel outbreak with high attack rate
  • A dynamic COVID-19 immune signature includes associations with poor prognosis
  • Management of post-acute covid-19 in primary care.

and more >>>

17 August

The Top 10 >>>

  • Household Transmission of SARS-CoV-2 in the United States
  • Chemotherapy and COVID-19 Outcomes in Patients With Cancer
  • The Covid-19 Pandemic and the Incidence of Acute Myocardial Infarction

and more >>>

16 August

The Top 10 >>>

  • Plasma from recovered COVID-19 subjects inhibits spike protein binding to ACE2 in a microsphere-based inhibition assay
  • Duration of infectiousness and correlation with RT-PCR cycle threshold values in cases of COVID-19, England, January to May 2020
  • Baricitinib: Impact on COVID-19 coagulopathy?

and more >>>

15 August

The Top 10 >>>

  • Survival of SARS-COV-2 under liquid medium, dry filter paper and acidic conditions
  • A negative COVID-19 test does not mean recovery
  • Tocilizumab among patients with COVID-19 in the intensive care unit: a multicentre observational study

and more >>>

14 August

The Top 10 >>>

  • Antibody prevalence for SARS-CoV-2 following the peak of the pandemic in England: REACT2 study in 100,000 adults
  • Robust T cell immunity in convalescent individuals with asymptomatic or mild COVID-19
  • Risk factors for COVID-19-related mortality in people with type 1 and type 2 diabetes in England: a population-based cohort study

and more >>>

13 August

The Top 10 >>>

  • Management of post-acute covid-19 in primary care
  • Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding
  • Host polymorphisms may impact SARS-CoV-2 infectivity

and more >>>

12 August

The Top 10 >>>

  • Phase 1/2 study of COVID-19 RNA vaccine BNT162b1 in adults
  • Single-cell landscape of immunological responses in patients with COVID-19
  • Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans

and more >>>

11 August

The Top 10 >>>

  • Stefano Lazzari: Prevention
  • Approaches and Challenges in SARS-CoV-2 Vaccine Development
  • Molecular and Immunological Diagnostic Tests of COVID-19: Current Status and Challenges

and more >>>

10 August

The Top 10 >>>

  • Interferon responses in viral pneumonias
  • Improved clinical symptoms and mortality among patients with severe or critical COVID-19 after convalescent plasma transfusion
  • A molecular pore spans the double membrane of the coronavirus replication organelle

and more >>>

9 August

The Top 10 >>>

  • Successful Elimination of Covid-19 Transmission in New Zealand
  • Prevalence of SARS-CoV-2 Antibodies in Health Care Personnel in the New York City Area
  • COVID-19–Associated Multisystem Inflammatory Syndrome in Children — United States, March–July 2020

and more >>>

8 August

The Top 10 >>>

  • Clinical characteristics and predictors of outcomes of hospitalized patients with COVID-19 in a multi-ethnic London NHS Trust: a retrospective cohort study
  • Digital technologies in the public-health response to COVID-19
  • Where Do the Children Play?

and more >>>

7 August

The Top 10 >>>

  • SARS-CoV-2 viral load predicts COVID-19 mortality
  • Systems-level immunomonitoring from acute to recovery phase of severe COVID-19
  • Severe COVID-19 is marked by a dysregulated myeloid cell compartment

and more >>>

6 August

The Top 10 >>>

  • The risk of COVID-19 transmission in train passengers: an epidemiological and modelling study
  • SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness
  • Changes in the Number of US Patients With Newly Identified Cancer Before and During the Coronavirus Disease 2019 (COVID-19) Pandemic

and more >>>

5 August

The Top 10 >>>

  • First results of the seroprevalence survey about SARS-CoV-2 (Italy, 64,000 participants)
  • Relationship of George Floyd protests to increases in COVID-19 cases using event study methodology
  • Acute SARS-CoV-2 infection impairs dendritic cell and T cell responses

and more >>>

4 August

The Top 10 >>>

  • SARS-CoV2 Serological Survey in Mumbai
  • Structural and functional properties of SARS-CoV-2 spike protein: potential antivirus drug development for COVID-19
  • Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans

and more >>>

3 August

The Top 10 >>>

  • SARS-CoV-2 Transmission and Infection Among Attendees of an Overnight Camp
  • Immune complement and coagulation dysfunction in adverse outcomes of SARS-CoV-2 infection
  • Distinct early serological signatures track with SARS-CoV-2 survival

and more >>>

2 August

The Top 10 >>>

  • Epidemiological and clinical characteristics of the COVID-19 epidemic in Brazil
  • Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy

and more >>>

1 August

The Top 10: Immunology >>>

Today, revise what you have studied over the past months. A summary of articles about Immunology and Vaccines since the beginning.

more >>>

 

Home | Daily TOP 10 | April | May | June | July | August | TOP 10 BOOK (PDF)