First Anniversary of COVID Reference

One year ago, we published the first edition of COVID Reference. It was a document on the fulminant accumulation of clinical knowledge about an emergent infectious disease in the previous three months. At that time, treatment strategies were tentative, the unutterable hydroxychloroquine was still en vogue, the multisystem inflammatory syndrome in children (MISC) as yet unheard of, and nobody knew about Long COVID or variants.

Since then, we have come a long way. An ultra-connected and worldwide cooperating science community has discovered – sometimes to their own surprise – how much they can achieve in a short time. Today, 15 months into the pandemic, more than 300 million people have been vaccinated. The development of these ultra-potent SARS-CoV-2 vaccines will be remembered as a milestone in medicine. They have opened new horizons and set a new benchmark for future pandemics.

Download the PDF of the first COVID Reference edition and travel back in time:

One year ago, on 30 March, we also started the daily presentation of important scientific papers: The first article we presented was by Anthony Fauci, Clifford Lane and Robert Redfield. Even after one year of hitherto inconceivable progress, the paper is still an excellent read:

Fauci AS, Lane HC, Redfield RR. Covid-19 – Navigating the Uncharted. N Engl J Med. 2020 Mar 26;382(13):1268-1269. PubMed: Full-text:


We have been continuing our daily coverage of outstanding “top” scientific papers for 365 consecutive days, always with the help of Rob Camp, our number one fan and copy editor. Continue with us every evening at or follow us on Twitter: Let’s go on hopefully for a calmer COVID-19 2021.

Bernd Sebastian Kamps & Christian Hoffmann